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Notes
      3. Old stuff
          3.1. Old pharm stuff (pre 2009)
              3.1.1. Scrap
 3.1.1.3. Adrenergic antagonists 
 1. Prazosin

Adrenergic antagonists

[PHW2:Chp14]

Classification

Alpha antagonists

  • Non-selective alpha antagonists
    * Phentolamine
    * Phenoxybenzamine
  • Selective alpha1 antagonists
    * Prazosin
  • Selective alpha2 antagonists
    * Yohimbine

 

NB:

Phenoxybenzamine

[PHW2:p221]

Active metabolite which forms covalent bond to alpha receptors
--> Irreversible blockade

Used in preoperative management of phaeochromocytoma

 

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Revised at 2007/02/21 01:12