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Notes
      3. Old stuff
          3.1. Old pharm stuff (pre 2009)
              3.1.3. Pharmacology
                  3.1.3.4. Local anaesthetics
 3.1.3.4.6. Eutectic mixture of local anaesthetics (EMLA) 

Eutectic mixture of local anaesthetics (EMLA)

[???]

 

Eutectic mixture - melting point of the mixture is lower than the melting points of the individual component

EMLA (eutectic mixture of local anaesthetics)

2.5% of lidocaine and 2.5% prilocaine

pH 9.6 (adjuected by NaOH)

Melting point of 16C

Oil-based (cream) --> Allows higher concentration of anaesthetics

Duration = 2 hours

 

 

Skin harvesting requires 2 hours application

45 min application for venipuncture, lumbar puncture

 

Methaemoglobin level increase in children <3 years due to foetal erythrocyte deficient in methaemoglobin reductase

Not for wound or mucous membranes

 

Causes vasoconstriction

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Revised at 2007/02/23 00:34