3. Old stuff
          3.1. Old pharm stuff (pre 2009)
              3.1.4. Physiology
                  3.1.4.7. Fluids
 3.1.4.7.2. Extracellular fluid 

Extracellular fluid (ECF)

(see also [Fluid compartments])

Functional ECF

  • Water in bone and dense connective tissues, and water in transcellular compartment move more slowly and not considered in acute fluid shifts.
  • Functional ECF = the rest of ECF (plasma + ISF)

Thus,

  • ICF to Functional ECF = 55:27.5 = 2:1 (approx)

 

Typical electrolyte concentration in some transcellular fluids (mmol/L)

  • Saliva
    * Na+ = 20-80
    * K+ = 10-20
    * Cl- = 20-40
    * HCO3- = 20-60
  • Gastric juice
    * Na+ = 20-100
    * K+ = 5-10
    * Cl- = 120-160
    * HCO3- = 0
  • Pancreatic juice
    * Na+ = 120
    * K+ = 5-10
    * Cl- = 10-60
    * HCO3- = 80-120
  • Bile
    * Na+ = 150
    * K+ = 5-10
    * Cl- = 40-80
    * HCO3- = 20-40
  • Ileal fluid
    * Na+ = 140
    * K+ = 5
    * Cl- = 105
    * HCO3- = 40
  • Colonic fluid
    * Na+ = 140
    * K+ = 5
    * Cl- = 85
    * HCO3- = 60
  • Sweat
    * Na+ = 65
    * K+ = 8
    * Cl- = 39
    * HCO3- = 16
  • CSF
    * Na+ = 147
    * K+ = 3
    * Cl- = 113
    * HCO3- = 25