By maintaining blood flow
Blood pressure
Good BP does NOT mean
Good blood flow
Normal volume
Essential for perfusion of
Brain
Kidney
Normal volume
Adequate cardiac function
Optimising cardiac preload
Decisions to make
Choice of fluid
Amount
Timing
Volume effects of colloids is context sensitive
90% volume effects during acute bleeding
40% volume effect when normovolemic
During acute bleeding, volume effect of colloids ≥ 90%
When normovolemic, volume effect of colloids ≈ 40%
Crystalloid preloading has no major effects
Monitoring
Perioperative weight gain
CVP
Pulmonary artery occlusion pressure (PAOP)
aka "wedge" pressure
Arterial line trace "swing"
Variation in systolic blood pressure and pulse pressure with positive pressure ventilation
≥5 mmHg during one positive pressure mechanical breath is significant
Strong predictor of positive response to a colloid volume challenge
Dynamic fluid challenge
A fixed volume of colloid (e.g. 100-200mL)
No change or decrease after fluid challenge
Covert hypovolaemia
Need more colloid
Sustained increased of ≥3 mmHg in CVP or PAOP
Intravascular compliance has been reached
Cease fluid challenge
TOE monitor
Repeated boluses of colloid to maximize stroke volume
SE of overhydration
PONV
May be worsened with dehydration
Overhydration does not improve PONV
Wound infection
Risk factors
Impaired tissue oxygenation
Mild hypothermia
Wound healing
Oedema adversely affct flap outcome in plastic and flap surgery
Intestinal oedema
Associated with
Delayed gut recovery
Risk of bacterial translocation
Risk of multiple organ dysfunction syndrome
Abdominal compartment syndrome
Recommendation
No more than 2.5 - 3L of crystalloids in the 24 hours post-op
Replace blood loss with colloid or blood
Avoid
No dextran in trauma
No albumin in traumatic head injury