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Notes
      3. Old stuff
          3.1. Old pharm stuff (pre 2009)
              3.1.3. Pharmacology
                  3.1.3.1. Pharmacology principles
                      3.1.3.1.2. Pharmacodynamics
                          3.1.3.1.2.2. Mechanism of drug actions
                              3.1.3.1.2.2.1. Receptors
 3.1.3.1.2.2.1.3. Receptor occupancy theory 

Receptor occupancy theory

[Ref: SH4:p22]

Traditionally...

  • The intensity of effect of a drug is proportional to the fraction of receptors occupied by the durg.
    --> Maximal drug effect occurs when all receptors are occupied.
  • Flaw: Does not account for antagonist or partial agonist.
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Table of contents  | Bibliography  | Index
Revised at 2007/02/11 23:37