Bartonella

Facultative intracelluar parasites

Bartonella quintana

Causes trench fever - mild, relapsing fever with maculopapular rash

Reservoir - human

Vector - human body lice

Treatment: Azithromycin

Bartonella henselae

Associated with most cases of cat-scratch disease

Small abscesses at site of cat scratch or bite

   -> followed by fever and localised lymphadenopathy

Also causes bacillary angiomatosis in immunocompromised pts.

Treatment: Doxycycline plus rifampicin

Bartonella bacilliformis

Causes Oroya fever

   -> Serious, infectious anaemia

Vector - sandfly. Primarily in South America

Treatment: Blood transfusion, azithromycin

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