3.1.4.4.1.1.2. Coagulation cascade
A.1.3. Coagulation cascade
- Conversion of plug into definitive clot is by formation of insoluble fibrin from soluble plasma protein fibrinogen
- Fibrin initially is a loose mesh of interlacing strands
- Stabilisation is when this loose mesh is converted to a tight and dense aggregate via formation of covalent cross-linkages