183 / 795
3. 
3.1.3.10.2. Table - IV induction agents IV anaesthetic agents
| Vd (L/kg) | PB | Clearance | Elimination halflife |
CSHT (8 hrs) |
pK | Acid/base | pH | Induction dose | |
| Propofol | 3.5 - 4.5 L/kg | 98% | 30 - 60 mL/kg/min | 0.5 - 1 hours | <40min | 11 | Acid |
7 - 8.5 (Diprivan) 4.5 - 6.4 (Generic) |
1 - 2.5 mg/kg |
| Thiopentone | 2.5 L/kg | 80% | 3.4 mL/kg/min | 11.6 hours | 3 hours | 7.6 | Acid | 10.5 | 3 - 5 mg/kg |
| Methohexitone | 2.2 L/kg | 10.9 mL/kg/min | 3.9 hours | > 7.6 | Acid | ||||
| Ketamine | 2.5 - 3.5 L/kg | 20-50% | 16 - 18 mL/kg/min | 2 - 3 hours | 7.5 | 3.5 - 5.5 | 1 - 2 mg/kg IV | ||
| Etomidate | 2.2 - 4.5 L/kg | 76% | 10 - 20 mL/kg/min | 2 - 5 hours | 4.2 | Base |
6.9 (Propylene glycol) 8.1 ( |
0.2 - 0.4 mg/kg | |
| Midazolam | 1 - 1.5 L/kg | 96 - 98% | 6 - 8 mL/kg/min | 1 - 4 hours | 6.15 | 3.5 | 0.1 - 0.2 mg/kg |
NB:
- Ketamine induction dose
* 1 - 2 mg/kg IV for induction
* 4 - 8 mg/kg IM for induction
* 0.2 - 0.5 mg/kg IV for analgesia