182 / 795
3. 
3.1.3.10.1. Table - Inhalational Anaesthetics Inhalational anaesthetics
| Blood:gas | Oil:gas | MAC | MAC awake | MW | Boiling point | Vapour pressure | |
| Halothane | 2.54 | 224 | 0.75% | 0.55 MAC | 197 | 50.2C | 244 mmHg |
| Enflurane | 1.90 | 1.63% | 184 | 56.5C | 172 mmHg | ||
| Isoflurane | 1.46 | 98 | 1.17% | 0.38 MAC | 184 | 48.5C | 240 mmHg |
| Desflurane | 0.42 | 19 | 6.60% | 0.34 MAC | 168 | 22.8C | 669 mmHg |
| Sevoflurane | 0.69 | 47 | 1.80% | 0.34 MAC | 200 | 58.5C | 170 mmHg |
| N2O | 0.46 | 1.4 | 104% | 0.64 MAC | 44 | -88.5C | gas |
| Xenon | 0.115 | 71% | 131 | -108C | gas | ||
| Comment |
|
NB:
- Boiling points (in descending order):
* S (58.5C)
* E (56.5C)
* H (50.2C)
* I (48.5C)
* D (22.8C)
* Mneumonic for boiliing points: Sevoflurane is higher than desflurane - Vapour pressure:
* Desflurane has the highest vapour pressure (669 mmHg) at 20C
* Sevoflurane has the lowest (170 mmHg) at 20C) (excluding N2O and Xenon) - Blood:gas coefficient points for isoflurane and N2O are 1.46 and 0.46 respectively
- N2O is more soluble in blood than desflurane (0.46 vs 0.42), but much less soluble in oil (1.4 vs 19)
- MAC awake to MAC ratio
* N2O has the highest
* Desflurane and N2O has the lowest - N2O has a critical temperature of 36.5C, and critical pressure is 72 Bar
* [PHW2]