3. Old stuff
          3.2. Old physio stuff (around 2005)
              3.2.4. Clinical measurement
                  3.2.4.1. Basic principles
 3.2.4.1.2. Flow 

Flow

Keypoints

For laminar flow

  • Hagen-Poiseuille equation
    i.e. Flow = Pressure x r4pi/8nl
  • Resistance proportional to viscosity
    * Not affected by density
  • Viscosity make laminar flow more likely

For turbulent flow

  • R changes with flow
  • Resistance affected by density
    * Not affected by viscosity
  • Density make turbulent flow more likely

Laminar flow

Principle

  • Laminar flow occurs when stream lines of the flow are parallel to the sides of the tube
  • Laminar flow proportional to 1/viscosity
  • Laminar flow proportional to the 4th power for radius
  • Axial flow moves twice as fast as mean velocity
  • Longitudinal velocity profile is of a parabola.
  • Density of gas is NOT relevant to laminar flow rate

Flow calculation

For pure laminar flow,
--> Pressure (cmH2O) = Flow (L/sec) x Resistance

where

  • Resistance = 8 nl/r4pi
    * n = viscosity
    * l = length
    * r = radius
    * unit = cmH2O.L-1.sec
    * unit = kPa.L-1.sec

Hagen-Poiseuille equation

Laminar flow = Pressure x r4(pi)/8nl

  • Only applies to
    * Newtonian fluids (motion does not affect dynamic viscosity)
    * Steady flow
    * Laminar flow
  • Blood is non-Newtonian and viscosity changes with flow

Turbulent flow

Principle

  • Resistance is NOT constant
    * R changes with flow
  • Pressure proportional to approx. (flow rate)2
  • Greater resistance when flow is turbulent, everything else being equal.
  • Pressure proportional density of gas
  • Pressure inversely proportional to the 5th power of radius
    * i.e. Fanning equation
  • Viscosity of gas is NOT relevant to turbulent flow rate

Reynold's number (Re)

Formula

Re = DV x (d/n)

  • D = diameter
  • V = mean velocity
  • d = density
  • n = viscosity
  • Dimensionless (no units)

Significance

  • When Re>3000
    --> predominantly turbulent flow
  • When Re<2000
    --> predominantly laminar flow

Thus,

  • Ratio of density:viscosity (d:n) are the inherent properties of gas that contribute to Re
  • Turbulence more likely with higher velocity and diameter

Additional notes

Conductance

Conductance = 1/resistance
* Unit for conductance = L.cmH2O-1.sec-1

Entrance length

Entrance length - the distance required for laminar flow to be established
= 0.03 x diameter x Re

Viscosity

Viscosity
= ratio of shear stress to shear rate of the fluid

Unit for viscosity
--> dynes/cm2

Custom fields
1 :20050527
2 :20050604
3 :20050527
Bibliography