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Notes
      3. Old stuff
          3.2. Old physio stuff (around 2005)
              3.2.3. Physiology
                  3.2.3.6. Haematology
                      3.2.3.6.2. Transfusion medicine
                          3.2.3.6.2.3. Blood storage
 3.2.3.6.2.3.1. Plasma preparations 

Plasma preparations

[Ref: PK1:p255]

Fresh frozen plasma

... is prepared from fresh blood and frozen rapidy to be stored at -30C

  • Used for replacement of coagulation factors
  • Shelf-life of 1 year

Cryoprecipitate

... is produced from freshly separated plasma by freezing at -70C, followed by thawing at 4C

Cryoprecipitate is rich in

  • Factor 8
    * ~ 80 units
  • Fibrinogen
  • Fibrinectin
    * ~ 250mg

NB:

Normal fibrinogen level = 3g/L [???]

Freeze-dried factor 8 concentrate

  • Lyophilized preparation from FFP
  • Stored at 4C
  • Contains large amounts of factor 8, and small amounts of fibrinogen
  • Higher risk of transmitting hepatitis

Freeze-dried factor 9 concentrate

  • Used for treatment of factor 9 deficiency (Christmas disease, or Haemophilia B)
  • Also contains factors 2, 7, 10

 

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Table of contents  | Bibliography  | Index
Revised at 2007/03/09 16:32